Glucosamine Chondroitin - Benefits and side effects of Glucosamine Chondroitin Supplements


Glucosamine chondroitin sulfates are substances which are found in the body naturally. Glucosamine is one of the forms of amino sugar that plays an important role in the cartilage repair and formation. Chondroitin sulfate gives elasticity to the cartilage and a part of a large protein molecule. These both are available in the market as nutritional and dietary supplements. They are obtained from animal tissue such as glucosamine from lobster, crab or shrimp shells and chondroitin sulfate is obtained from animal cartilage like shark or tracheas cartilage. They both are considered as the building blocks for proteoglycans and enhance building of new collagen.

These both supplements also reduce pain of those people who are suffering from osteoarthritis within several weeks or months. Glucosamine makes the cartilage more rigid and stronger. Glucosamine is also available in various chemical forms such as glucosamine sulfate and glucosamine hydrochloride.

How does Glucosamine Chondroitin Sulfate work?

Studies shows that these supplements act as a pain relief for patients suffering from mild to moderate osteoarthritis and help in reducing pain in just few weeks. It has a similar effect as compared to nonsteroidal anti-inflammatory drugs like ibuprofen and aspirin. According to research, these supplements also reduce the damage done to cartilage in people suffering from osteoarthritis. Chondroitin promotes elasticity in cartilage and water retention and prohibits enzymes which break down the cartilage. These supplements are also used in the treatment of degenerative joint disease.

Ingredients in Glucosamine Chondroitin

  • Glucosamine Sulfate - 1500mg
  • Chondroitin Sulfate - 1200mg
  • Methsulfonylmethane - 2000mg

Other ingredients are Stearic acid, Gelatin and Magnesium stearate. It contains no wheat, salt, corn, dairy, sugar, yeast, soy, artificial colors, preservatives or flavors.

Recommended Dosage

Before taking these supplements, one should consult the doctor about the appropriate dosage. One should take about 1500mg of glucosamine per day and about 1200mg of chondroitin sulfate per day for 6-8 weeks along with the medication.

Benefits of Glucosamine Chondroitin

  • It is very helpful in maintaining connective tissues and healthy joints.
  • It is beneficial for patients with osteoarthritis.
  • It is beneficial for skin, hairs and nails.

Side Effects of Glucosamine Chondroitin

One can experience increase in softened stools and intestinal gas with the use of these supplements.

Definition of Glucosamine:

Glucosamine can be defined as an amino sugar which is known to be a prominent precursor in several bio-chemical syntheses of various lipids and glycosylated proteins. Glucosamine forms part of the combined structure of chitin and polysaccharides chitosan. It has been found out that it is one of the most abundant monosaccharides. Commercial production of glucosamine is one of the most profitable businesses in the modern world. It is usually produced by observing fermentation of grains or hydrolysis of exoskeleton of several crustaceans. 

Different health effects related to Glucosamine:

Administration of glucosamine can be used for treating the problem of arthritis along with prevention of cartilaginous degeneration. The compound is even used for treating osteoarthritis. Glucosamine has significant benefits for functional as well as pain impairment. It is even used during conjunction and latest medical studies have suggested that the compound is effective in increasing efficacy. It is also used in veterinary sciences and also during the placebo treatment. There are thus several beneficial aspects concerning glucosamine. Furthermore, it has a stimulating effect on the rate of glucose metabolism, thereby reducing the chances of obesity within an individual. It is also known for is anti-inflammatory properties. 

Allergy related to Glucosamine:

Though mostly the compound glucosamine offers beneficial effects on the human body, yet there are certain allergies too that may be related to the compound. The compound may cause insulin resistance within the body thereby lowering down excessively the blood sugar level, which result in the individual feeling light and extremely weak. The compound may even cause lowering down the rate of production of proteolytic enzyme and therefore causing disbalance in the catabolic activities within the body. Furthermore, it may even cause degradation of liposomal enzymes. Thus there are significant allergies related to this compound. Though the normal level of intake of glucosamine is 1800 mg per day, yet the exact level for individuals should only be administered after a briefing with the doctor.


People suffering from diabetes should not take this supplement. One should consult the doctor while using this supplement if one is allergic to shellfish.

Pregnant women and children should not take this supplement as women can have adverse effects on a child or on a developing fetus.

One should not take chondroitin sulfate along with the aspirin therapy or blood-thinning medication.


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